Growth Factor Delivery Through Self-assembling Peptide Scaffolds
نویسندگان
چکیده
منابع مشابه
P 99: Self-Assembling Peptide Scaffolds as New Therapeutic Method in TBI: Focused on Bioactive Motifs
Traumatic brain injury (TBI) is a common reason of brain tissue loss as a result of tumors, accidents, and surgeries. Renewal of the brain parenchyma is restricted by many reasons such as inimical substances produced as the result of trauma and also inflammatory responses. A strong cascade of inflammatory responses begins as a result of TBI which include recalling peripheral leukocytes into the...
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Cutaneous wound repair regenerates skin integrity, but a chronic failure to heal results in compromised tissue function and increased morbidity. To address this, we have used an integrated approach, using nanobiotechnology to augment the rate of wound reepithelialization by combining self-assembling peptide (SAP) nanofiber scaffold and Epidermal Growth Factor (EGF). This SAP bioscaffold was tes...
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Amphiphilic self-assembling peptides are functional materials, which, depending on the amino acid sequence, the peptide length, and the physicochemical conditions, form a variety of nanostructures including nanovesicles, nanotubes, and nanovalves. We designed lipid-like peptides with an aspartic acid or lysine hydrophilic head and a hydrophobic tail composed of six alanines (i.e., ac-A6K-CONH2,...
متن کاملp 99: self-assembling peptide scaffolds as new therapeutic method in tbi: focused on bioactive motifs
traumatic brain injury (tbi) is a common reason of brain tissue loss as a result of tumors, accidents, and surgeries. renewal of the brain parenchyma is restricted by many reasons such as inimical substances produced as the result of trauma and also inflammatory responses. a strong cascade of inflammatory responses begins as a result of tbi which include recalling peripheral leukocytes into the...
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ژورنال
عنوان ژورنال: Clinical Orthopaedics & Related Research
سال: 2011
ISSN: 0009-921X
DOI: 10.1007/s11999-011-1891-1